为什么这段代码点击开始没有任何反应

爱学习的同学

import pygame
from pygame.locals import *
import sys

pygame.init()
WIDTH = 600
HEIGHT = 300


screen = pygame.display.set_mode((WIDTH,HEIGHT))

pygame.display.set_caption("表情包闯关")

background = pygame.image.load(r'C:\Users\Administrator\Desktop\对话游戏\image\main_image.jpg').convert()
kaishi = pygame.image.load(r'C:\Users\Administrator\Desktop\对话游戏\image\1.jpg').convert()
kaishi_rect = kaishi.get_rect()
jieshu = pygame.image.load(r'C:\Users\Administrator\Desktop\对话游戏\image\2.jpg').convert()
jieshu_rect = jieshu.get_rect()   
running = 3
kaishi_rect.left, kaishi_rect.top = (WIDTH - kaishi_rect.width) // 2, 50
screen.blit(kaishi, kaishi_rect)
pygame.display.flip()
if pygame.mouse.get_pressed()[0]:
      pos = pygame.mouse.get_pos()
      if kaishi_rect.left < pos[0] <  kaishi_rect.right and \
                    kaishi_rect.top < pos[1] <  kaishi_rect.bottom:
            running = 3 - 1
while running == 2:
    print("1")
      

爱学习的同学

这是一个游戏开始界面 点击开始游戏后没有任何反应